Filters
Sensor Target Type Specificity Sensor Name Sensor Type Analysis Technique IV Propertiessort descending Organism Binding Protein Fluorophore PIs
Ions

Zn2+

CALWY

FRET-based biosensors Merkx M
Metabolites

PtdIns(3,4,5)P3

GFP-PHBtk

Translocation-based biosensors Balla T
Kinase Activity

Protein kinase A

AKAR1-34

FRET-based biosensors HEK293 cells Various Tsien RY, Zhang J, Zhang J
Metabolites

PtdIns(4)P

Pippi-PI(4)P

FRET-based biosensors MDCK cells Matsuda M
Ions

Ca2+

Pericams

Single FP-based extrinsic biosensors Tsien RY, Miyawaki A, Campbell RE
Protein Activation and Conformation

Rho family GTPase activation

Raichu-RhoA

FRET-based biosensors Matsuda M
Ions

Zn2+

eCALWYs

FRET-based biosensors Pancreatic beta-cells Rutter GA, Merkx M
Metabolites

PtdIns(3,4,5)P3

GFP-PHCRAC

Translocation-based biosensors Snyder SH
Kinase Activity

Protein kinase A

CRY-AKAR

FRET-based biosensors HeLa cells Cerulean, mVenus, mCherry Zhang J
Metabolites

PtdIns3P

GFP-FYVEEEA1

Translocation-based biosensors Emr SD
Ions

Ca2+

GCaMPs

Single FP-based extrinsic biosensors Tsien RY, Imoto K, Kotlikoff MI, Looger LL, Campbell RE, Harvey BK
Metabolites

cGMP

CGYs

FRET-based biosensors confocal flourescence microscopy CHO-K1 cells, HEK-293 cells PKG-Ia binding eCFP, eYFP Umezawa Y
Protein Activation and Conformation

Rho family GTPase activation

Raichu-RBD

FRET-based biosensors Matsuda M
Ions

Zn2+

Cys2His2

FRET-based biosensors Neurons Palmer AE
Metabolites

PtdIns(3,4,5)P3

GFP-Ent3p

Translocation-based biosensors Letourneur F
Kinase Activity

Protein kinase B/Akt

BKAR

FRET-based biosensors NIH 3T3 mCFP, mYFP Newton AC
Metabolites

PtdIns3P

GFP–p40phox iPX

Stephens LR
Ions

Ca2+

Case12/16

Single FP-based extrinsic biosensors Tsien RY, Chudakov DM, Campbell RE
Metabolites

cGMP

cGES sensors

FRET-based biosensors confocal flourescence microscopy HEK-293 cells GAF-B domain of PDE2A and GAF-A domain of PDE5A eCFP, eYFP Lohse MJ
Protein Activation and Conformation

Rho family GTPase activation

Raichu-RalA

FRET-based biosensors COS-7 cells CFP, YFP Matsuda M
Ions

Zn2+

ZapCY

FRET-based biosensors HELA cells (Cytosol, Golgi, ER) Palmer AE
Metabolites

PtdIns(3,4,5)P3

CAY

FRET-based biosensors Swiss 3T3 fibroblasts Allen PG
Kinase Activity

Protein kinase B/Akt

Aktus

FRET-based biosensors CHO cells CFP, YFP Umezawa Y
Metabolites

PtdIns4P

GFP-PHOSH2

Translocation-based biosensors confocal microscopy Levine TP
Ions

Ca2+

Camgaroos

Single FP-based extrinsic biosensors Tsien RY, Campbell RE

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