Filters
Sensor Target Type Specificitysort descending Sensor Name Sensor Type Analysis Technique IV Properties Organism Binding Protein Fluorophore PIs
Metabolites

glutamate

FLIPE sensors

FRET-based biosensors confocal flourescence microscopy, spectroscopy KD 630 nM Rat hippocampal cells, PC12 cells glutamate/aspartate binding protein ybeJ from Escherichia coli eCFP, Venus Frommer WB, Frommer WB
Metabolites

glutamate

GluSnFR

FRET-based biosensors Tsien RY
Metabolites

glutamate

FLIP-cpGltI210

FRET-based biosensors Ito T
Metabolites

glutamate

FRET glutamine reporter

FRET-based biosensors Ludewig U
Metabolites

glutamate

FLIP-cpGlnH183

FRET-based biosensors Ito T
Ions

halide ions

YFP-H148Q

Single FP-based intrinsic biosensors Verkman AS
Ions

halide ions

YFP-H148QI152L

Single FP-based intrinsic biosensors Verkham AS
Ions

Hg2+

eGFP205C

Single FP-based intrinsic biosensors Sagermann M
Ions

Hg2+

IFP/BV sensor

Single FP-based intrinsic biosensors Tang Y
Metabolites

histidine

FLIP-HisJ/cpHisJ194

FRET-based biosensors Ito T
Kinase Activity

Histone H3 phosphorylation

H3 phosphorylation reporter

FRET-based biosensors inverted epiflourescence microscopy HeLa cells CFP, YFP Ting AY
Enzyme Activity (Non-Kinase)

histone H4 lysine acetylation

Histac (K5, K7)

FRET-based biosensors CFP, YFP(venus) Yoshida M
Enzyme Activity (Non-Kinase)

histone H4 lysine acetylation

Histac-K12 (K12)

FRET-based biosensors confocal microscopy COS7 cells CFP, YFP(venus) Yoshida M
Enzyme Activity (Non-Kinase)

histone lysine methylation

K9 reporter

FRET-based biosensors MEF cells CFP, YFP Ting AY
Enzyme Activity (Non-Kinase)

histone lysine methylation

K27 reporter

FRET-based biosensors Ting AY
Metabolites

inositol 1,4,5-trisphosphate

LIBRA

FRET-based biosensors Mikoshiba K
Metabolites

inositol 1,4,5-trisphosphate

FIRE1-3

FRET-based biosensors Mignery GA
Metabolites

inositol 1,4,5-trisphosphate

IRIS-1

FRET-based biosensors Tojyo Y
Kinase Activity

Insulin Receptor

Phocus

FRET-based biosensors Immunofluorescence microscopy CHO-IR cells eCFP, eYFP Umezawa Y
Kinase Activity

Insulin Receptor

Phocus-2pp

FRET-based biosensors CHO-IR cells eCFP, eYFP Umezawa Y
Protein Activation and Conformation

Insulin receptor activation

Sinphos

Single FP-based extrinsic biosensors CHO-IR cells, CHO-K1 cells CFP(cpFP), GFP(cpFP) Umezawa Y
Metabolites

leucine

FLIP-LivJ/cpLivJ261

FRET-based biosensors Ito T
Protein Activation and Conformation

M(1) muscarinic receptor (M(1)R) activation

M1R-YFP-CFP

FRET-based biosensors fluorescence microscopy tsA-201 cells eCFP, eYFP Hille B
Metabolites

maltose

FLIPmal sensors

FRET-based biosensors confocal flourescence microscopy arabinose FLIP Kd-200 nM,maltose FLIP Kd-40 µM Escherichia coli BL21-Gold(DE3) cells periplasmic binding protein for arabinose or maltose, E. coli high-affinity L-arabinose binding protein AraF eCFP, eYFP (venus) Frommer WB
Protein Activation and Conformation

MAP kinase-activated protein kinase 2 conformation

GMB

FRET-based biosensors HEK293 cells, Swiss 3T3 cells eCFP, eBFP Gaestel M

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