Filters
Sensor Target Typesort ascending Specificity Sensor Name Sensor Type Analysis Technique IV Properties Organism Binding Protein Fluorophore PIs
Metabolites

PtdIns(4,5)P2:Ins(1,4,5) P3 dynamics

GFP-PHPLC-

Translocation-based biosensors Nash MS
Metabolites

cAMP

HCN2-camps

FRET-based biosensors confocal flourescence microscopy, FRAP cAMP-sensitive HEK 293a cells, mouse heart single cAMP binding of HCN2 channel- a helices covering cAMP binding site eCFP, eYFP Engelhardt S
Metabolites

PtdIns(3,4,5)P3

YFP-PHTAPP1

Translocation-based biosensors Alessi DR
Metabolites

PtdIns(4,5)P2:Ins(1,4,5) P3 dynamics

CYPHR (FRET: PLC activity)

Translocation-based biosensors Shapiro L
Metabolites

cAMP

(T)Epac(VV)

FRET-based biosensors FLIM, confocal fluorescence microscopy cAMP indicators Hek293 cells, N1E-115, human HeLa cells (ccl-2) cAMP binding mTurquise (mECFPD-Epac(CD, and DEP)-cp173Venus-Venus Jalink K
Metabolites

PtdIns(3,4,5)P3

GFP-Svp1p

Translocation-based biosensors Lemmon MA
Metabolites

PtdIns(4,5)P2:Ins(1,4,5) P3 dynamics

FP-Tubby

Translocation-based biosensors Meyer T
Metabolites

cGMP

FlincG

Single FP-based extrinsic biosensors Dostmann WR
Metabolites

PtdIns(3,4,5)P3

GFP-PHBtk

Translocation-based biosensors Balla T
Metabolites

PtdIns(4,5)P2:Ins(1,4,5) P3 dynamics

FP-PHPLCδ1(FRET)

Translocation-based biosensors Meyer T
Mechanical Force

Mechanical strain

VinTS

FRET-based biosensors confocal microscopy BAECs, MEF cells, HEK293 cells mTFP1, venus(A206K) Schwartz MA
Mechanical Force

Mechanical strain

stFRET

FRET-based biosensors Dictyostelium , HS1, AX2 GFP, eGFP Uyeda TQ
Mechanical Force

Mechanical strain

PriSSM (PRIM-based)

FRET-based biosensors BAECs, HEK cells Cerulean, Venus Sachs F
Mechanical Force

Mechanical strain

sstFRET

FRET-based biosensors confocal microscopy HEK-293, 3T3, C.Elegans Cerulean, Venus Sachs F
Kinase Activity

Protein kinase A

CRY-AKAR

FRET-based biosensors HeLa cells Cerulean, mVenus, mCherry Zhang J
Kinase Activity

Protein kinase B/Akt

BKAR

FRET-based biosensors NIH 3T3 mCFP, mYFP Newton AC
Kinase Activity

Protein kinase B/Akt

Aktus

FRET-based biosensors CHO cells CFP, YFP Umezawa Y
Kinase Activity

Protein kinase B/Akt

Akind

FRET-based biosensors COS-7 cells CFP, YFP Matsuda M
Kinase Activity

Protein kinase B/Akt

GFP-PKB-RFP

FRET-based biosensors NIH 3T3 GFP, RFP Larijani B
Kinase Activity

Protein kinase B/Akt

ReAktion

FRET-based biosensors NIH 3T3 CFP, YFP Zhang J
Kinase Activity

Protein kinase B/Akt

AktAR

FRET-based biosensors NIH 3T3 Cerulean, cpV E172 Zhang J
Kinase Activity

Protein kinase C

CKAR; KCP-1

FRET-based biosensors Schultz C, Newton AC
Kinase Activity

Abl

Crk-based reporter

FRET-based biosensors confocal flourescence microscopy, spectroscopy Kinase Specific (tyrosine) NIH 3T3, MEF cells complete chicken c-CrkII gene eCFP, eYFP (citrine) Tsien RY
Kinase Activity

Protein kinase D

DKAR

FRET-based biosensors COS-7 cells, HeLa Cells mCFP, mYFP Newton AC
Kinase Activity

Abl

EGFR indicator

FRET-based biosensors confocal flourescence microscopy, spectroscopy Kinase Specific, sensitive to concentration of EGF B82, NIH 3T3, HeLa cells SH2 domain (residues 374–465) from mouse p52 Shc eCFP, eYFP (citrine) Tsien RY

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