Filters
Sensor Target Type Specificity Sensor Namesort ascending Sensor Type Analysis Technique IV Properties Organism Binding Protein Fluorophore PIs
Ions

Zn2+

ZinCh

FRET-based biosensors Merkx M
Ions

Zn2+

ZapCY

FRET-based biosensors HELA cells (Cytosol, Golgi, ER) Palmer AE
Ions

pH

YFpH

Single FP-based intrinsic biosensors Miyazaki S
Metabolites

PtdIns(3,4)P2

YFP-PHTAPP1

Translocation-based biosensors Alessi DR
Metabolites

PtdIns(3,5)P2

YFP-PHTAPP1

Translocation-based biosensors Alessi DR
Metabolites

PtdIns(3,4,5)P3

YFP-PHTAPP1

Translocation-based biosensors Alessi DR
Ions

halide ions

YFP-H148QI152L

Single FP-based intrinsic biosensors Verkham AS
Ions

halide ions

YFP-H148Q

Single FP-based intrinsic biosensors Verkman AS
Redox and Voltage

voltage

VSFPs

FRET-based biosensors Knöpfel T, Knöpfel T, Knöpfel T, Knöpfel T
Redox and Voltage

voltage

VSFP-cpEGFP

FRET-based biosensors Sakai R, Isacoff EY
Mechanical Force

Mechanical strain

VinTS

FRET-based biosensors confocal microscopy BAECs, MEF cells, HEK293 cells mTFP1, venus(A206K) Schwartz MA
Ions

Ca2+

TN-XXL

FRET-based biosensors Griesbeck O, Miyawaki A, Persechini A, Ikura M
Mechanical Force

Mechanical strain

stFRET

FRET-based biosensors Dictyostelium , HS1, AX2 GFP, eGFP Uyeda TQ
Mechanical Force

Mechanical strain

sstFRET

FRET-based biosensors confocal microscopy HEK-293, 3T3, C.Elegans Cerulean, Venus Sachs F
Kinase Activity

Src

Srcus

FRET-based biosensors HeLa cells, MEF cells CFP, YFP Chien S
Kinase Activity

Src

Src reporter

FRET-based biosensors MCF-7 cells CFP, YFP Umezawa Y
Kinase Activity

Abl

Src indicator

FRET-based biosensors confocal flourescence microscopy, spectroscopy Kinase Specific (tyrosine) NIH 3T3, HeLa Cells Rous sarcoma virus Src gene (residues148–245) eCFP, eYFP (citrine) Tsien RY
Redox and Voltage

voltage

SPARC

Single FP-based extrinsic biosensors Pieribone VA, Sakai R, Isacoff EY
Protein Activation and Conformation

Insulin receptor activation

Sinphos

Single FP-based extrinsic biosensors CHO-IR cells, CHO-K1 cells CFP(cpFP), GFP(cpFP) Umezawa Y
Redox and Voltage

redox

rxYFP149202

Single FP-based intrinsic biosensors YFP Winther JR
Redox and Voltage

redox

roGFPs

Single FP-based intrinsic biosensors HeLa, P388D1, or HL60 cells, HeLa and PC3 cells roGFP Remington SJ, Tsien RY, Remington SJ, Papa FR
Protein Activation and Conformation

Rho family GTPase activation

RhoA biosensor commentary

FRET-based biosensors Hahn KM, Hahn KM
Redox and Voltage

redox

Redoxfluor

FRET-based biosensors CHO cells Cerulean, Citrine Sakai Y
Kinase Activity

Protein kinase B/Akt

ReAktion

FRET-based biosensors NIH 3T3 CFP, YFP Zhang J
Protein Activation and Conformation

Akt conformation

ReAktion

FRET-based biosensors fluorescence microscopy NIH3T3 fibroblasts human Akt-1/protein kinase B-a eCFP, Citrine Zhang J

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