Filters
Sensor Target Type Specificity Sensor Namesort descending Sensor Type Analysis Technique IV Properties Organism Binding Protein Fluorophore PIs
Ions

Ca2+

jRCaMP1a, b

Single FP-based extrinsic biosensors Cultured neurons mRuby Kim DS
Ions

Ca2+

jRGECO1a

Single FP-based extrinsic biosensors Cultured neurons mApple Kim DS
Enzyme Activity (Non-Kinase)

histone lysine methylation

K27 reporter

FRET-based biosensors Ting AY
Enzyme Activity (Non-Kinase)

histone lysine methylation

K9 reporter

FRET-based biosensors MEF cells CFP, YFP Ting AY
Metabolites

inositol 1,4,5-trisphosphate

LIBRA

FRET-based biosensors Mikoshiba K
Metabolites

BAI2 (a furanosyl borate diester)

LuxP-FRET

FRET-based biosensors spectroscopy, fluorescence microscopy BAI2 Kd 270 nM Escherichia coli BL21 (luxS-), V. harVeyi strains BB120 (wild-type), MM30 (luxS-), MM32 (luxS-, luxN-) LuxP-BAI2 binding CFP, YFP Sayre R
Protein Activation and Conformation

M(1) muscarinic receptor (M(1)R) activation

M1R-YFP-CFP

FRET-based biosensors fluorescence microscopy tsA-201 cells eCFP, eYFP Hille B
Ions

Cu+

Mac1-FRET

FRET-based biosensors fluorescence microscopy, spectroscopy Cu+ sensitive Yeast cells, E.coli Copper (I) binding domain CFP, YFP He C
Kinase Activity

Glucokinase

mCerulean-GCK-mVenus

FRET-based biosensors confocal flourescence microscopy BTC3 cells YFP Rizzo MA
Redox and Voltage

voltage

Mermaid

FRET-based biosensors Neuro2A cells CFP, YFP Miyawaki A
Protein Activation and Conformation

ERK conformation

Miu2

FRET-based biosensors HeLa cells, COS-7 cells, 293F CFP, YFP, RFP(Dropna) Matsuda M
Kinase Activity

Extracellular signal-regulated kinase (ERK)

Miu2

FRET-based biosensors HeLa cells CFP, YFP Matsuda M
Redox and Voltage

redox (H2O2)

mt-cpYFP

Single FP-based extrinsic biosensors confocal microscopy human osteosarcoma cells cpYFP Cheng H
Ions

pH

mtAlpHi

Single FP-based intrinsic biosensors Pozzan T
Metabolites

NAD+

none

Single FP-based extrinsic biosensors venus Goodman RH
Enzyme Activity (Non-Kinase)

O-GlcNAc transferase

O-GlcNAc sensor

FRET-based biosensors HeLa cells eCFP, Venus Mahal LK
Metabolites

ATP:ADP ratio

Perceval

Single FP-based extrinsic biosensors Yellen G
Metabolites

NADH

Peredox

Single FP-based extrinsic biosensors cpT-Sapphire Yellen G
Ions

Ca2+

Pericams

Single FP-based extrinsic biosensors Tsien RY, Miyawaki A, Campbell RE
Metabolites

PtdIns(4,5)P2

PHOSBP

Translocation-based biosensors confocal microscopy COS-7 cells GFP, mRFP Balla T, Munro S
Metabolites

PtdIns4P

PHOSBP

Translocation-based biosensors confocal microscopy COS-7 cells GFP, mRFP Balla T, Munro S
Ions

pH

pHluorins

Single FP-based intrinsic biosensors Rothman JE
Kinase Activity

Insulin Receptor

Phocus

FRET-based biosensors Immunofluorescence microscopy CHO-IR cells eCFP, eYFP Umezawa Y
Kinase Activity

Insulin Receptor

Phocus-2pp

FRET-based biosensors CHO-IR cells eCFP, eYFP Umezawa Y
Ions

pH

pHRed

Single FP-based intrinsic biosensors Yellen G

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