Filters
Sensor Target Type Specificity Sensor Name Sensor Type Analysis Technique IV Propertiessort descending Organism Binding Protein Fluorophore PIs
Ions

Hg2+

eGFP205C

Single FP-based intrinsic biosensors Sagermann M
Metabolites

inositol 1,4,5-trisphosphate

FIRE1-3

FRET-based biosensors Mignery GA
Redox and Voltage

voltage

VSFPs

FRET-based biosensors Knöpfel T, Knöpfel T, Knöpfel T, Knöpfel T
Metabolites

PtdIns(3,5)P2

GFP-Svp1p

Translocation-based biosensors Lemmon MA
Protein Activation and Conformation

Annexin A4 self-association

CYNEX4

FRET-based biosensors confocal flourescence microscopy, FRAP HeLa cells, N1E-115, MDCK2 neuroblastoma cells Annexin A4 (Ca2+ regulated phospholated) eCFP, eYFP Schultz C
Ions

Hg2+

IFP/BV sensor

Single FP-based intrinsic biosensors Tang Y
Metabolites

inositol 1,4,5-trisphosphate

IRIS-1

FRET-based biosensors Tojyo Y
Redox and Voltage

voltage

Mermaid

FRET-based biosensors Neuro2A cells CFP, YFP Miyawaki A
Metabolites

PtdIns(3,5)P2

GFP-PHBtk

Translocation-based biosensors Balla T
Protein Activation and Conformation

CaMKII conformation

CamuiαamCYCaMIIα

FRET-based biosensors two-photon fluorescence microscopy HeLa cells YFP(Venus) , CFP (S175G) Schultz C, Hayashi Y
Ions

pH

ECFP

Single FP-based intrinsic biosensors Tsien RY, Verkman AS
Metabolites

leucine

FLIP-LivJ/cpLivJ261

FRET-based biosensors Ito T
Redox and Voltage

voltage

FlaSh-CFP/YFP

FRET-based biosensors salamander retinal cones, on-bipolar cells, horizontal cells, wide-field amacrine cells eGFP, GFPuv, and wtGFP, eCFP and eYFP Isacoff EY
Metabolites

PtdIns(3,5)P2

GFP-Ent3p

Translocation-based biosensors Letourneur F
Protein Activation and Conformation

ERK conformation

Miu2

FRET-based biosensors HeLa cells, COS-7 cells, 293F CFP, YFP, RFP(Dropna) Matsuda M
Ions

pH

EYFP

Single FP-based intrinsic biosensors Tsien RY, Verkman AS
Redox and Voltage

voltage

PROPS

Single FP-based intrinsic biosensors E.coli Proteorhodopsin Cohen AE
Metabolites

PtdIns(4,5)P2

GFP-ARNO

Translocation-based biosensors Czech MP
Metabolites

ATP:ADP ratio

Perceval

Single FP-based extrinsic biosensors Yellen G
Protein Activation and Conformation

Estrogen receptor ligand binding domain conformation

CEY

FRET-based biosensors COS-7 cells, Sf9 cells, Hf7c cells ER-Ligand binding domain seCFP, eYFP Lannigan DA
Ions

pH

E2GFP

Single FP-based intrinsic biosensors Beltram F
Metabolites

NO

FRET-MT

FRET-based biosensors Levitan ES
Regulated Proteolysis

Cell cycle progression

Fucci

Single FP-based extrinsic biosensors COS-7 cells, HeLa Cells RFP, GFP Miyawaki A
Metabolites

PtdIns(4,5)P2

GFP-Cytohesin-1

Translocation-based biosensors Czech MP
Protein Activation and Conformation

G protein activation

FP-Gα/FP-Gβ(γ)

FRET-based biosensors HeLa cells, HEK cells, HEK293T, Dictyostelium discoideum cells, FRT cells, haploid yeast cells YFP(Gaq-mYFP) and CFP(mTq), YFP and CFP, eYFP Gadella TW Jr, Lohse MJ, Bünemann M, Gilman AG, Bünemann M, Devreotes P, Scarlata S, Simon MI

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